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Anti P62 Antibodies Information

Anti-p62 antibodies (AP62A) are found in a primary biliary cirrhosis.[1] p62 is also more frequent in Stage IV primary biliary cirrhosis and is prognostic for severe disease.[2][3] The autoantigen is the nucleoporin 62kDA protein.

References

  1. ^ Wesierska-Gadek J, Hohenuer H, Hitchman E, Penner E (1996). "Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis". Gastroenterology 110 (3): 840–7. doi:10.1053/gast.1996.v110.pm8608894. PMID 8608894.
  2. ^ Miyachi K, Hankins RW, Matsushima H, et al. (2003). "Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis: a multicenter study". J. Autoimmun. 20 (3): 247–54. doi:10.1016/S0896-8411(03)00033-7. PMID 12753810.
  3. ^ Invernizzi P, Selmi C, Ranftler C, Podda M, Wesierska-Gadek J (2005). "Antinuclear antibodies in primary biliary cirrhosis". Semin. Liver Dis. 25 (3): 298–310. doi:10.1055/s-2005-916321. PMID 16143945.
· · Medical test: Antibodies: autoantibodies
Anti-nuclear antibody

PBC: Anti-gp210 · Anti-p62 · Anti-sp100

ENA: Anti-topoisomerase/Scl-70 · Anti-Jo1 · ENA4 (Anti-Sm, Anti-nRNP, Anti-Ro, Anti-La)

Anti-centromere

Anti-dsDNA
Anti-mitochondrial antibody Anti-cardiolipin
Anti-cytoplasm antibody Anti-neutrophil cytoplasmic (C-ANCA, P-ANCA) · Anti-smooth muscle (Anti-actin) · Anti-TPO/Antimicrosomal
Cell membrane Anti-ganglioside · Anti-GBM
Extracellular Anti-thrombin · Lupus anticoagulant · Anti-transglutaminase · Anti-gliadin · RA (Rheumatoid factor/anti-IgG, Anti-citrullinated peptide)
Multiple locations Anti-phospholipid · Anti-apolipoprotein

: LMC

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Categories: Autoantibodies | PBC Autoantibodies

 

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